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dc.contributor.otherUCH. Departamento de Ciencias Biomédicas-
dc.contributor.otherProducción Científica UCH 2021-
dc.creatorStromsnes, Kristine.-
dc.creatorLagzdina, Rudite.-
dc.creatorOlaso González, Gloria.-
dc.creatorGimeno Mallench, Lucía.-
dc.creatorGambini, Juan.-
dc.date2021-
dc.date.accessioned2022-04-02T04:00:41Z-
dc.date.available2022-04-02T04:00:41Z-
dc.date.issued2021-08-23-
dc.identifier.citationStromsnes, K., Lagzdina, R., Olaso-Gonzalez, G., Gimeno-Mallench, L. & Gambini, J. (2021). Pharmacological properties of polyphenols: bioavailability, mechanisms of action, and biological effects in In vitro studies, animal models, and humans. Biomedicines, vol. 9, i. 8 (23 aug.), art. 1074. DOI: https://doi.org/10.3390/biomedicines9081074-
dc.identifier.issn2227-9059 (Electrónico)-
dc.identifier.urihttp://hdl.handle.net/10637/13600-
dc.descriptionEste artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/2227-9059/9/8/1074-
dc.descriptionEste artículo de investigación pertenece al número especial "Oxidative Stress and Inflammation: From Mechanisms to Therapeutic Approaches 2.0".-
dc.description.abstractDrugs are bioactive compounds originally discovered from chemical structures present in both the plant and animal kingdoms. These have the ability to interact with molecules found in our body, blocking them, activating them, or increasing or decreasing their levels. Their actions have allowed us to cure diseases and improve our state of health, which has led us to increase the longevity of our species. Among the molecules with pharmacological activity produced by plants are the polyphenols. These, due to their molecular structure, as drugs, also have the ability to interact with molecules in our body, presenting various pharmacological properties. In addition, these compounds are found in multiple foods in our diet. In this review, we focused on discussing the bioavailability of these compounds when we ingested them through diet and the specific mechanisms of action of polyphenols, focusing on studies carried out in vitro, in animals and in humans over the last five years. Knowing which foods have these pharmacological activities could allow us to prevent and aid as concomitant treatment against various pathologies.-
dc.formatapplication/pdf-
dc.language.isoen-
dc.language.isoes-
dc.publisherMDPI-
dc.relationEste artículo de investigación ha sido financiado a través de ayudas del Instituto de Salud Carlos III (CB16/10/00435 (CIBERFES)), del Ministerio de Ciencia e Innovación (MICINN) del Gobierno de España (PID2019-110906RB-I00/AEI/10.13039/501100011033), de la Consellería de Sanitat de la Generalitat Valenciana (PROMETEO/2019/097) y de la EU Funded H2020-DIABFRAIL-LATAM (Ref: 825546), European Joint Programming Initiative “A Healthy Diet for a Healthy Life” (JPI HDHL), and of the ERA-NET Cofund ERA-HDHL (GA No. 696295 of the EU Horizon 2020 Research and Innovation Program). Parte de los equipamientos utilizados en esta investigación han sido financiados por la Generalitat Valenciana y co-financiados con el Fondo Europeo de Desarrollo Regional (FEDER) (OP ERDF of Comunitat Valenciana 2014-2020).-
dc.relation.ispartofBiomedicines, vol. 9, n. 8 (23 aug. 2021)-
dc.rightshttp://creativecommons.org/licenses/by/4.0/deed.es-
dc.subjectFenoles - Propiedades.-
dc.subjectPhenols - Properties.-
dc.subjectFenoles - Efectos fisiológicos.-
dc.subjectPharmacology.-
dc.subjectMedicamentos - Biodisponibilidad.-
dc.subjectDrugs - Bioavalability.-
dc.subjectFarmacología.-
dc.subjectPhenols - Physiological effect.-
dc.titlePharmacological properties of polyphenols : bioavailability, mechanisms of action, and biological effects in In vitro studies, animal models, and humans-
dc.typeArtículo-
dc.identifier.doihttps://doi.org/10.3390/biomedicines9081074-
dc.relation.projectIDCB16/10/00435-
dc.relation.projectIDPID2019-110906RB-I00/AEI/10.13039/501100011033-
dc.relation.projectIDPROMETEO/2019/097-
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