Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10637/13601
Título : Lipid peroxidation in subretinal fluid : some light on the prognosis factors
Autor : Bosch Morell, Francisco.
García Gen, Enrique.
Mérida Donoso, Salvador.
Penadés Fons, Mariola.
Desco Esteban, Ma. Carmen.
Navea Tejerina, Amparo.
Materias: Estrés oxidativo.Oxidative stress.Miopía.Retinal detachment.Retina - Desprendimiento.Fluidos corporales.Body fluids.Myopia.
Fecha de publicación : 30-mar-2021
Editorial : MDPI
Citación : Bosch-Morell, F., García-Gen, E., Mérida, S., Penadés, M., Desco, C. & Navea, A. (2021). Lipid peroxidation in subretinal fluid: some light on the prognosis factors. Biomolecules, vol. 11, i. 4 (30 mar.), art. 514. DOI: https://doi.org/10.3390/biom11040514
Resumen : The aim of this study was to identify a relation between the clinical characteristics and differences in lipid peroxidation in the subretinal fluid (SRF) of rhegmatogenous retinal detached patients by malondialdehyde (MDA) quantification. We collected 65 SRF samples from consecutive patients during scleral buckling surgery in rhegmatogenous retinal detachment (RRD) eyes. In addition to a complete ophthalmic evaluation, we studied the refractive status, evolution time, and the number of detached retinal quadrants to establish the extension of RRD.We studied the clinical aspects and oxidative stress and compared the characteristics among groups. We found that neither the evolution time of RRD nor the patients’ age correlated with the MDA concentration in the SRF. The MDA and the protein content of the SRF increased in the patients with high myopia and with more extended RRD. Our results suggest that oxidative imbalance was important in more extended retinal detachment (RD) and in myopic eyes and should be taken into account in the managing of these cases.
Descripción : Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/2218-273X/11/4/514
Este artículo de investigación pertenece al número especial "Molecular Pathology, Diagnostics and Therapeutics of Retinal Diseases".
Idioma: en
es
URI : http://hdl.handle.net/10637/13601
Derechos: http://creativecommons.org/licenses/by/4.0/deed.es
ISSN : 2218-273X (Electrónico)
Aparece en las colecciones: Dpto. Ciencias Biomédicas

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