Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10637/13609
Registro completo de metadatos
Campo DC Valor Lengua/Idioma
dc.contributor.otherProducción Científica UCH 2021-
dc.contributor.otherUCH. Departamento de Ciencias Biomédicas-
dc.creatorReula Martín, Ana.-
dc.creatorPitarch Fabregat, Javier.-
dc.creatorMilara, Javier.-
dc.creatorCortijo Gimeno, Julio.-
dc.creatorMata Roig, Manuel.-
dc.creatorMilian Medina, Lara.-
dc.creatorArmengot, Miguel.-
dc.date2021-
dc.date.accessioned2022-04-05T04:00:24Z-
dc.date.available2022-04-05T04:00:24Z-
dc.date.issued2021-07-20-
dc.identifier.citationReula, A., Pitarch-Fabregat, J., Milara, J., Cortijo, J., Mata-Roig, M., Milian, L. & Armengot, M. (2021). High-speed video microscopy for Primary Ciliary Dyskinesia diagnosis: a study of ciliary motility variations with time and temperature. Diagnostics, vol. 11, i. 7 (20 jul.), art. 1301. DOI: https://doi.org/10.3390/diagnostics11071301-
dc.identifier.issn2075-4418 (Electrónico)-
dc.identifier.urihttp://hdl.handle.net/10637/13609-
dc.descriptionEste artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/2075-4418/11/7/1301-
dc.descriptionEste artículo de investigación pertenece al número especial "Progress in Diagnosing and Managing Primary Ciliary Dyskinesia".-
dc.description.abstractPrimary ciliary dyskinesia (PCD) is a rare disease resulting from a defect in ciliary function that generates, among other issues, chronic upper and lower respiratory tract infections. European guidelines recommend studying ciliary function (pattern (CBP) and frequency (CBF)), together with characteristic clinical symptoms, as one of the definitive tests. However, there is no “gold standard”. The present study aims to use high-speed video microscopy to describe how CBF and CBP alter over time and at different temperatures to reduce the error rate in the diagnosis of PCD. Samples of nasal epithelium from 27 healthy volunteers were studied to assess CBF and CBP at 0, 3, 24, 48, and 72 h, at room temperature and 4 C. It was observed that CBF increased while CBP became dyskinetic, both at room temperature and at 4 C, as time passed, especially after 3 h. In order to preserve all ciliary function parameters and to perform a reliable analysis to improve the diagnostic process of PCD, analysis should be performed within the first 3 h of sample collection, preferably in reference centers.-
dc.formatapplication/pdf-
dc.language.isoen-
dc.language.isoes-
dc.publisherMDPI-
dc.relationEste trabajo de investigación fue financiado por el Fondo Europeo de Desarrollo Regional (FEDER), por el Instituto de Salud Carlos III (FIS PI16/01315, FIS PI17/02158, FIS PI19/00949, JR18/00050, SAF2017-82913-R), por el CIBERES (CB06/06/0027) del Gobierno de España y por una beca PROMETEO 2017/023/UV de la Generalitat Valenciana.-
dc.relation.ispartofDiagnostics, vol. 11, n. 7 (20 jul. 2021)-
dc.rightshttp://creativecommons.org/licenses/by/4.0/deed.es-
dc.subjectMicroscopy.-
dc.subjectMicroscopia.-
dc.subjectKartagener, Síndrome de - Diagnóstico.-
dc.subjectKartagener's syndrome - Diagnosis.-
dc.subjectPrimary ciliary dyskinesia - Diagnosis.-
dc.subjectAparato respiratorio - Enfermedades en los niños.-
dc.subjectPediatric otolaryngology.-
dc.subjectOtorrinolaringología pediátrica.-
dc.subjectEnfermedades crónicas en los niños.-
dc.subjectRespiratory organs - Diseases in children.-
dc.subjectChronic diseases in children.-
dc.subjectDisquinesia ciliar, Síndrome de - Diagnóstico.-
dc.titleHigh-speed video microscopy for Primary Ciliary Dyskinesia diagnosis : a study of ciliary motility variations with time and temperature-
dc.typeArtículo-
dc.identifier.doihttps://doi.org/10.3390/diagnostics11071301-
dc.relation.projectIDFIS PI16/01315-
dc.relation.projectIDFIS PI17/02158-
dc.relation.projectIDFIS PI19/00949-
dc.relation.projectIDJR18/00050-
dc.relation.projectIDSAF2017-82913-R-
dc.relation.projectIDCB06/06/0027-
dc.relation.projectID2017/023/UV-
Aparece en las colecciones: Dpto. Ciencias Biomédicas

Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
High-speed_Reula_DIAGNOSTICS_2021.pdf11,71 MBAdobe PDFVisualizar/Abrir



Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.